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While cysteine, which is formed by the transsulfuration pathway from homocysteine and is therefore an indirect measure of the function of the methionine cycle, glutathione formation requires additional steps for its formation and is not directly a component of the cycles related to S-adenosyl methionine

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Despite these tremendous advances in diagnostic and therapeutic armamentarium, the conduct of thyroid disorders is still hampered by several limitations and challenges that include the difficulties of early and correct diagnosis-especially for autoimmune thyroid diseases-side effects of the current treatment modalities and imprecision in personalized care (Jacob et al